Common questions about microdosing LSD

Selected search terms that lead people to my site. Disclaimer: I am not a scientist. These answers are based on years of experience dosing myself and dosing with other people.

Bridget Riley

Can you dose after microdosing? How much time should you space between doses?

Everyone is different. I’ve dosed the day after microdosing. I’ve microdosed the day after microdosing. I always felt the effects. It always went well. Some people report short-term tolerance and the need to take a little more to feel an equivalent effect the day after a (micro)dose, but I wouldn’t necessarily advise that here. Wait a few days if you can between doses. Or, figure out why you may feel the need to dose so often.

(The Fadiman microdosing regimen recommends one day on, three days off. So if you want to take a big trip within a microdosing regimen, try sticking to on/off days, whether the dose is micro or not.)

How long will it last and how quickly will I feel it? 

Depends on the size of the dose. Some people take so little that they feel nothing, just slightly happier and more focused throughout the day. I usually took 10-15mcg, so I’d feel something (more present, content, lifted, creative) within 20-45 minutes and it would typically last several hours. For me, 6-8 hours.

Why am I sleepy on a microdose? Why am I wired on a microdose?

Most people get energy from microdosing acid and may have a hard time sleeping or resting a few hours from the onset. However, I’ve taken recreational quarters at night many times and have been able to sleep at a reasonable hour. Some friends, not so much. We still don’t have a way to know how each and every person should dose because everyone reacts in their own way. I may even react differently to the same dose given my mental circumstances at the time. Some people report mania and anxiety from microdosing and studies have shown possible increases in neuroticism.

Fatigue from microdosing is not common, so if you’re feeling sleepy, you are likely truly exhausted and need to rest. Psychedelics can make you more aware of your self, your body, its needs and processes.

If you get too anxious/manic or exhausted/depleted on a microdose, it may be good to halt future use or seek help in case of emergency.

Can I mix a microdose with prescription drugs, like Adderall or Vyvanse?

You possibly could, but probably shouldn’t. Even mixing caffeine with a microdose can be too much and cause anxiety/increased heart rate. Slow your role. Protect your heart.

How will microdosing impact my sex drive? Continue reading “Common questions about microdosing LSD”


Could the examination of psychedelic interpretations across women and men aid understanding of biological/developmental/cultural sex differences? Could it empower both sexes to know more about this?

Why I quit microdosing

Published in Human Parts

Illustration by

Switching gears along the Yarra River, I pedal faster and faster, heading nowhere in particular. My face just crashed into a party of flies and now I’m swallowing wings. Sinking into my surroundings — the wind, ripples in the water, parrots overhead — with no thoughts of all the elses and elsewheres I could be, I’m tripping.

This microdose feels like a half tab. Which isn’t necessarily bad, except I can’t focus. I can’t sit still. I can’t read the lines of a book without being bombarded by my own. I can’t write. All I can do is keep going and going. Moving through. This is not what I anticipated for a Wednesday morning. Continue reading “Why I quit microdosing”

Dosing after microdosing

Moving from psychedelic routine to spot-treatment, originally published on Medium

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Kristina Johnson

Fifteen micrograms of acid, on a sliver of paper, washed down with a glass of water. This is my medicine of choice.


I microdosed 1P-LSD from April to December 2017 following a regimen: one day on, threeish days off. It’s been over a year since I stopped that routine and tapered my dosing to as-needed for mood support.

Eight months is a bit longer than most ~microdosing experts~ recommend. Online sources typically suggest six weeks or three months, but that’s mostly speculative. Any recommendations for continued psychedelic use (and all psychiatric medicine?) are relatively inexpert given our still premature understanding of the brain. When it comes to intimate psychological issues, there is no single cure for what has complex—and largely unknown—causes. No one knows which precise treatment or prescription will work for anyone. Especially in people with discreet or hard-to-diagnose issues, who experience difficulty communicating, or who are especially young or old. It’s all an experiment. That’s what the medical community has been doing, as well as a few rogue individuals.

Testing, and reflecting. Continue reading “Dosing after microdosing”